An essential vaccination for defending infants against Meningococcal Group B (MenB) disease — a dangerous and potentially fatal bacterial infection — is the Bexsero vaccine. MenB can cause septicaemia (blood poisoning) and meningitis (inflammation of the brain lining), both of which can worsen quickly and result in long-term problems or even death if left untreated.
This article covers the significance, timing, benefits, side effects, and safety of the Bexsero vaccine for infants.
What is the Bexsero Vaccine?
The Bexsero vaccine protects against Neisseria meningitidis serogroup B, one of the main causes of bacterial meningitis in infants and young children. It works by training the immune system to recognise and fight the bacteria before it causes illness.
In many countries, Bexsero is included in routine childhood immunisation programs to reduce the risk of severe infection.
What Makes Bexsero Vital for Infants?
During their first year, babies are especially vulnerable to MenB. Early symptoms of the illness often resemble common viral infections like flu or fever, making early detection difficult. The Bexsero vaccine helps prevent this life-threatening disease and its potential long-term consequences such as:
- Brain damage
- Hearing loss
- Limb amputations
Baby Bexsero Vaccine Schedule
The typical Bexsero schedule for infants includes:
- First dose: at 2 months of age
- Second dose: at 4 months of age
- Booster dose: at around 12 months of age
In some cases, such as high-risk infants or disease outbreaks, an accelerated schedule may be recommended.
How Is the Vaccination Administered?
The Bexsero vaccine is given intramuscularly, usually in the baby’s thigh. It can be administered at the same time as other routine immunisations.
Since Bexsero may increase the likelihood of fever when given alongside other vaccines, doctors may recommend giving paracetamol (acetaminophen) afterwards to reduce discomfort.
Benefits of the Bexsero Vaccine
- Prevents Meningococcal B Disease: Offers targeted protection against a severe type of meningitis.
- Protects During a Vulnerable Period: Starts protecting infants as early as 2 months old.
- Reduces Emergency Hospitalisations: Helps avoid emergency or critical care admissions.
- Included in National Immunisation Programs: Adopted as part of regular childhood vaccination in many countries.
Typical Adverse Reactions in Infants
The Bexsero vaccine is generally safe and well-tolerated, though mild to moderate side effects can occur:
- Fever
- Redness, swelling, or tenderness at the injection site
- Increased crying or irritability
- Lethargy or drowsiness
- Loss of appetite
- Vomiting (less common)
These symptoms typically appear within a day and subside within 1–2 days.
Uncommon but Serious Side Effects
Although rare, serious side effects require immediate medical attention:
- High fever above 39.5°C (103°F)
- Febrile seizures (triggered by fever)
- Severe allergic reactions (rash, breathing difficulty, swelling of face or lips)
Report any unusual or severe symptoms to a healthcare provider without delay.
Monitoring and Aftercare
- Encourage rest and offer extra fluids after vaccination
- Use doctor-approved paracetamol to reduce fever or discomfort
- Observe the baby for high fever, rashes, persistent crying, or unusual behaviour
- Keep track of the child’s immunisation schedule and attend all booster appointments
When to Delay or Skip the Vaccine
The vaccine may be postponed or skipped in rare cases:
- If the baby had a severe allergic reaction to a previous dose or a vaccine ingredient
- If the baby has a high fever or serious illness at the time of the appointment
A healthcare professional will determine whether vaccination should be delayed or avoided.
Conclusion
The Bexsero vaccine is a crucial step in protecting infants from meningococcal Group B infection. While mild side effects are relatively common, they are short-lived and manageable. The vaccine’s benefits far outweigh the risks, making it a life-saving part of early childhood immunisation.
If you have concerns or questions about vaccines, consult your paediatrician. Being